Key Publications - Münster Center, Germany
- Schulze-Bahr E, Wang Q, Wedekind H, Haverkamp W, Chen Q, Sun Y, Rubie C, Hördt M, Towbin JA, Borggrefe M, Assmann G, Qu X, Somberg JC, Breithardt G, Oberti C, Funke H (1997). KCNE1 mutations cause Jervell and Lange-Nielsen syndrome. Nature Genet. 17: 267-268
- Chen Q, Kirsch GE, Zhang D, Brugada R, Brugada J, Brugada P, Potenza D, Moya A, Borggrefe M, Breithardt G, Ortiz-Lopez R, Wang Z, Antzelevitch C, O'Brien RE, Schulze-Bahr E, Keating MT, Towbin JA, Wang Q (1998) Genetic Basis and molecular mechanisms for idiopathic ventricular fibrillation. Nature 392: 293-926
- Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney G, Breithardt G, Keating MT, Towbin JA, Beggs AH, Brink P, Wilde AAM, Toivonen L, Zareba W, Robinson JL, Timothy KW, Corfield V, Wattanasirichaigoon D, Corbett C, Haverkamp W, Schulze-Bahr E, Lehmann MH, Schwartz K, Coumel P, Bloise R (2001) Genotype-phenotype correlation in the long QT syndrome. Gene-specific triggers for life-threatening arrhythmias. Circulation 103: 89-95
- Wedekind H#, Smits JPP#, Schulze-Bahr E, Arnold R#, Veldkamp MW, Bajanowski T, Borggrefe M, Funke H, Brinkmann B, Warnecke I, Bhuiyan ZA, Wilde AAM, Breithardt G, Haverkamp W (2001) A de-novo mutation in the SCN5A gene associated with early onset and sudden cardiac death in the first months of life. Circulation 104: 1158-1164
- Schwartz PJ, Priori SG, Bloise R, Napolitano C, Ronchetti E, Piccinini A, Goj C, Breithardt G, Schulze-Bahr E, Wedekind H, Nastoli J (2001) Molecular diagnosis in victims of Sudden Infant Death Syndrome. Medical and Legal Implications. Lancet 358: 1342-1343
- Smits JPP#, Eckardt L#, Probst V#, Brezzina CR, Schott JJ Remme CA, Haverkamp W, Breithardt G, Escande D, Schulze-Bahr E, Le Marec H, Wilde AAM (2002) Genotype-phenotype relationship in Brugada syndrome: Electrocardiographic features differentiate SCN5A-related patients from non SCN5A-related patients. J. Am. Coll. Cardiol. 40: 350-356
- Schulze-Bahr E, Neu A, Friederich P, B. Kaupp, Pongs O, Breithardt G, Isbrandt D (2003) Cardiac pacemaker dysfunction in a patient with inherited sinus node dysfunction. J. Clin. Invest. 111: 1537-1545
- Schulze-Bahr E, Eckardt L, Breithardt G, Seidl K, Wichter T, Wolpert C, Borggrefe M, Haverkamp W (2003) Sodium channel gene (SCN5A) mutations in 44 index patients with Brugada syndrome: Different incidences in familial and sporadic disease. Human Mut.: Mutation in Brief #615 (online)
- Gerull B#, Heuser A#, Wichter T, Paul M, Basson CT, McDermott DA, Lerman BB, Markowitz SM, Ellinor PT, MacRae CA, Peters S, Grossmann KS, Michely B, Sasse-Klaassen S, Birchmeier W, Dietz R, Breithardt G, Schulze-Bahr E, Thierfelder L (2004) Mutations in the desmosomal arm repeat protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nature Genet. 36: 1162-1164
- Eckardt L#, Probst V#, Smits JPP#, Schulze Bahr E, Wolpert C, Schimpf R, Wichter T, Boisseau P, Breithardt G, Borggrefe M, Le Marec H, Böcker D, Wilde AAM (2005) Long-term prognosis of individuals with right precordial ST elevation - Brugada syndrome. Circulation 111: 257-263
- Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A (2005) Brugada Syndrome. Report of the Second Consensus Conference. Circulation 111: 659-670
- Mönnig G, Eckardt L, Wedekind H, Haverkamp W, Milberg P, Kirchhof P, Assmann G, Breithardt, G, Schulze-Bahr E (2006) Electrocardiographic risk stratification in families with congenital long QT-syndrome. Eur. Heart J. 27: 2074-80.
- Imboden M, Swan H, Denjoy I, Van Langen I, Laitinen P, Napolitano C, Fressart V, Breithardt G, Berthet M, Priori S, Hainque B, Wilde AAM, Schulze-Bahr E, Feingold J, Guicheney P (2006) Female predominance and transmission distortion in long QT syndrome. New Engl. J. Med. (in press)
- Tan HL, Bardai A, Shimizu W, Moss AJ, Schulze-Bahr E, Noda T, Wilde AAM (2006) Genotype-specific onset of arrhythmias in congenital Long QT syndrome: possible therapy implications. Circulation 114: 2096-2103
- Choe C#, Schulze-Bahr E#, Neu A#,1,4, Xu J, Zhu ZI, Sauter K, Bähring R, Priori S, Guicheney P, Mönnig G, Neapolitano C, Heidemann J, Clancy CE, Pongs O, Isbrandt D (2006) C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3e. Hum. Mol. Genet. 15; 2888-2902