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Key Publications - Balitmore Center, United States


  1. Kao WH, Arking DE, Post W, Rea TD, Sotoodehnia N, Prineas RJ, Bishe B, Doan BQ, Boerwinkle E, Psaty BM, Tomaselli GF, Coresh J, Siscovick DS, Marbán E, Spooner PM, Burke GL, Chakravarti A. Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations. Circulation. 2009 Feb 24;119(7):940-51. Epub 2009 Feb 9.

  2. Chang KC , Barth AS , Sasano T , Kizana E , Kashiwakura Y , Zhang Y , Foster DB , Marbán E . CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4477-82. Epub 2008 Mar 12.

  3. Spooner PM. Sudden Cardiac Death: Influence of Diabetes. Diabetes Obesity , Metab. 2007 (epub ahead of print).

  4. Spooner PM. How will Genomic Approaches Translate into Clinical Applications, Dialogues in Cardiovascular Medicine. 2006,11; 213-223.

  5. Chang K-C. Barth AS, Sasano T, Zhang Y, Miake J, and Marbán E. CAPON Interacts with Neuronal NO Synthase to Modulate L-type Ca Current and Action Potential Duration in Ventricular Cardiomyocytes. Accepted for Presentation AHA 2007.

  6. Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marbán E, O'donnell CJ, Hirschhorn JN, Kaab S, Spooner PM, Meitinger T, Chakravarti A. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet. 2006 Jun;38(6):644-651. Epub 2006 Apr 30.

  7. Chang MG, Tung L, Sekar RB, Chang CY, Cysyk J, Dong P, Marbán E, Abraham MR. Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model. Circulation. 2006 Apr 18;113(15):1832-41. Epub 2006 Apr 10.

  8. Abraham MR, Henrikson CA, Tung L, Chang MG, Aon M, Xue T, Li RA, O' Rourke B, Marbán E. Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation. Circ Res. 2005 Jul 22;97(2):159-67. Epub 2005 Jun 23.

  9. Azene EM, Xue T, Marbán E, Tomaselli GF, Li RA. Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers. Cardiovasc Res. 2005 Aug 1;67(2):263-73. Epub 2005 Apr 21.

  10. Arking DE, Chugh SS, Chakravarti A, Spooner PM. Genomics in sudden cardiac death. Circ Res. 2004 Apr 2;94(6):712-23. Review.

  11. Spooner PM, Zipes DP. Sudden death predictors: an inflammatory association. Circulation. 2002 Jun 4;105(22):2574-6.

  12. Ennis IL, Li RA, Murphy AM, Marbán E, Nuss HB: Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility. J Clin Invest. 2002 Feb; 109(3): 393-400

  13. Marbán, E.: Cardiac channelopathies.  Nature. 2002 Jan 10; 415 (6868): 213-8. Review.

  14. Spooner PM, Albert C, Benjamin EJ, Boineau R, Elston RC, George AL Jr, Jouven X, Kuller LH, MacCluer JW, Marbán E, Muller JE, Schwartz PJ, Siscovick DS, Tracy RP, Zareba W, Zipes DP. Sudden cardiac death, genes, and arrhythmogenesis: consideration of new population and mechanistic approaches from a National Heart, Lung, and Blood Institute workshop, Part II. Circulation. 2001 May 22;103(20):2447-52.

  15. Myerburg RJ, Spooner PM. Opportunities for sudden death prevention: directions for new clinical and basic research. Cardiovasc Res. 2001 May;50(2):177-85. Review.